Emerging Applications of 3D Printing During CoVID 19 Pandemic by Unknown

Author:Unknown
Language: eng
Format: epub
ISBN: 9789813367036
Publisher: Springer Singapore

Lung-on-chip (LOC)

• Ability to mimic mechanical, chemical and biological properties associated with organ function

• Ability to replicate complex tissue architecture, especially the air-liquid interface (ALI)

• Highly tuned and controllable environment

• Can be designed to incorporate vasculature structure

• Can be multiplexed with other organ on chip systems to study drug and vaccine efficacy (Human on Chip)

• Time consuming and can be expensive to manufacture

• Choice of material to act as microfluidic chamber is crucial

• Requires additional equipment to maintain control over the microenvironment

• Inability to use all cell types

Benam et al. (2016)

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